High prevalences of anencephaly and neural tube defects (NTDs) have recently been recorded for several Texas counties bordering Mexico.
In addition, a few investigators have reported Hispanics to be at elevated risk for NTDs (anencephaly and spina bifida).
Factors contributing to this risk have not been established.
The authors conducted a study of NTDs in Harris County, Texas, to determine the prevalence of each defect.
Prevalence was established by identifying cases among resident live births and fetal deaths (stillbirths at =20 weeks) occurring from April 1,1989, through December 31,1991.
Using multiple case ascertainment methods, 59 cases of anencephaly and 32 cases of spina bifida were detected, resulting in prevalences of 3.8 (95% confidence interval 2.9-4.9) and 2.0 (95% confidence interval 1.4-2.8) per 10,000 live births, respectively.
The ratio of anencephaly prevalence to spina bifida prevalence was 2 : 1 in 1989,1 : 1 in 1990, and 3 : 1 in 1991, with a significant difference in 1991.
The female : male prevalence ratio was 1.0 for spina bifida and 2.2 for anencephaly, and was higher still for anencephaly among non-Hispanics (prevalence ratio=5.6).
For each defect, Hispanics experienced a prevalence approximately three times that of non-Hispanics.
This ethnic difference was greater for males with anencephaly and for females with spina bifida.
For anencephaly, the Hispanic : white/Anglo prevalence ratio (4.2) and the African-American : white/Anglo ...
Mots-clés Pascal : Spina bifida, Tube neural, Anencéphalie, Epidémiologie, Ethnie, Prévalence, Nourrisson, Homme, Texas, Etats Unis, Amérique du Nord, Amérique, Système ostéoarticulaire pathologie, Rachis pathologie, Maladie congénitale, Malformation, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Hispanique
Mots-clés Pascal anglais : Spina bifida, Neural tube, Anencephaly, Epidemiology, Ethnic group, Prevalence, Infant, Human, Texas, United States, North America, America, Diseases of the osteoarticular system, Spine disease, Congenital disease, Malformation, Nervous system diseases, Central nervous system disease, Cerebral disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0079227
Code Inist : 002B17D. Création : 199608.