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  1. Clinical science review : current aspects of thrombolytic therapy in women with acute myocardial infarction.

    Article - En anglais

    Acute myocardial infarction (AMI) remains the greatest threat to health in our society and is the most common cause of death in the United States and in many other Western industrialized countries.

    Recent data demonstrate that mortality from MI is continuing to decline.

    In these days of more aggressive management of acute MI (AMI) there has been a resurgence of interest in advances in thrombolytic therapy.

    However, observational studies of patients with AMI have shown that women sustaining an AMI have a worse prognosis than men.

    AMI is the number-one killer of women in the United States ; approximately 247,000 of more than 520,000 deaths due to AMI that occur each year are among women, and almost one-third of the women are younger than forty-five years old.

    While there have been great advances in thrombolytic therapy, these advances have benefited men to a more significant degree than they have benefited women.

    The purpose of this paper is to critically review the efficacy of thrombolytic therapy in women with AMI with consideration of some of the key components of its effectiveness : mortality, bleeding risk, infarct-artery patency, ventricular function, and cardiac arrhythmia.

    Mots-clés Pascal : Infarctus, Myocarde, Chimiothérapie, Fibrinolytique, Traitement, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Pronostic, Epidémiologie, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie

    Mots-clés Pascal anglais : Infarct, Myocardium, Chemotherapy, Fibrinolytic, Treatment, Human, Female, United States, North America, America, Prognosis, Epidemiology, Cardiovascular disease, Coronary heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0077193

    Code Inist : 002B02G. Création : 199608.