Effects of caffeine consumption on delayed conception.
The authors examined the effects of caffeine consumption on waiting time to conception in the Reproductive Health Study, a retrospective study of 1,430 non-contracepting, parous women interviewed between July 1989 and June 1990 at Fishkill, New York, and Burlington, Vermont.
Information was obtained on 2,501 pregnancies since 1980.
Women's reported consumption of caffeinated beverages during the first month of pregnancy was used to estimate daily caffeine intake, which was categorized as none, 1-150,151-300, and =301 mg.
Information on delayed conception was analyzed as a dichotomous variable (¾12 months delay vs.>12 months delay), and the per cycle probability of conception (fecundability) was estimated using waiting time to conception as a continuous variable.
Odds ratios of delayed conception and fecundability ratios adjusted for age, parity, smoking, last contraceptive used, infertility history, and race, were estimated by logistic regression and Cox proportional hazard models, respectively.
Women who did not smoke and who consumed no caffeine were used as a reference group.
The adjusted odds ratio of delayed conception for more than one year was not increased among women who consumed<300 mg of caffeine daily.
However, the odds ratio (OR) was 2.65 (95% confidence interval (CI) 1.38-5.07) among nonsmokers who consumed =301 mg of caffeine daily.
Although smoking per se was associated with a significant increased risk of delayed conception (OR=1.77,95% CI...
Mots-clés Pascal : Consommation, Café, Boisson stimulante, Toxicité, Conception, Temps attente, Rétrospective, Fertilité, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Homme
Mots-clés Pascal anglais : Consumption, Coffee, Stimulative beverage, Toxicity, Design, Waiting time, Retrospective, Fertility, Epidemiology, United States, North America, America, Human
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0070748
Code Inist : 002B03H. Création : 199608.