Dietary vitamin C and bêta-carotene and risk of death in middle-aged men : the Western Electric Study.
In the Western Electric Company Study, carried out in Chicago, Illinois, data on diet and other factors were obtained in 1958 and 1959 for a cohort of 1,556 employed, middle-aged men.
Nutrients included vitamin C and bêta-carotene.
An index that summarized combined intake of both nutrients was constructed.
Mean intakes of vitamin C in the lowest and highest tertiles of the index were 66 and 138 mg/day ; corresponding values for bêta-carotene were 2.3 and 5.3 mg/day.
A total of 522 of 1,556 men died during 32,935 person-years of follow-up, 231 from coronary heart disease and 155 from cancer.
After adjustment for potentially confounding factors, relative risks (95% confidence intervals) associated with an increment of 19 points in the index (difference between means of the lowest and highest tertiles) were 0.60 (0.39-0.93) for cancer mortality, 0.70 (0.49-0.98) for coronary disease mortality, and 0.69 (0.55-0.87) for all-cause mortality.
These results support the hypothesis that consumption of foods rich in vitamin C and bêta-carotene reduces risk of death in middle-aged men.
Mots-clés Pascal : Consommation alimentaire, Comportement alimentaire, Ascorbique acide, Vitamine, bêta-Carotène, Cardiopathie coronaire, Tumeur maligne, Mortalité, Homme, Epidémiologie, Antioxydant, Illinois, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Food intake, Feeding behavior, Ascorbic acid, Vitamin, Coronary heart disease, Malignant tumor, Mortality, Human, Epidemiology, Antioxidant, Illinois, United States, North America, America, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0070715
Code Inist : 002B30A01A2. Création : 199608.