This case-control study evaluates the relationship between leukemia and the work histories of active and retired employees of a large petroleum company.
The study includes 69 cases with leukemia and 284 matched controls.
Employment in production-related work in the oil and gas division was associated with myelogenous leukemia (odds ratio [OR]=2.0,95% confidence interval [CI]=97 to 4.2) and particularly with acute myelogenous leukemia (OR=2.8,95% CI=1.1 to 7.3).
The association with acute myelogenous leukemia was strongest for subjects in the highest tertile (32+years) of duration of employment in oil-and gas production-related work (OR=8. 7,95% CI=2.0 to 37), and there was a consistent trend of increasing ORs with increasing duration of employment (P=01).
No clear association was observed for refining division work and leukemia.
This is the first epidemiologic study reporting a positive association between oil and gas field work and acute myelogenous leukemia.
Mots-clés Pascal : Leucémie, Exposition professionnelle, Homme, Industrie pétrolière, Epidémiologie, Temps exposition, Activité professionnelle, Poste travail, Médecine travail, Hémopathie maligne, Histoire professionnelle
Mots-clés Pascal anglais : Leukemia, Occupational exposure, Human, Oil industry, Epidemiology, Exposure time, Professional activity, Workplace layout, Occupational medicine, Malignant hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0067111
Code Inist : 002B19B. Création : 199608.