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  1. Improving hypertension control among excessive alcohol drinkers : a randomised controlled trial in France.

    Article - En anglais


    To improve blood pressure control among hypertensive (>140/90 mmHg) excessive alcohol drinkers.


    Fourteen worksite physicians were randomised into an intervention group and a control group.

    The intervention was based on training the worksite physicians and follow up of those hypertensive subjects defined as excessive drinkers.

    Follow up was based on self monitoring of alcohol consumption by the subject, in view of the results of their gamma glutamyl transferase (GGT) activity determination.


    Fourteen workplaces in France-mainly in the industrial sector.


    Altogether 15 301 subjects were screened by the 14 physicians : 129 of these were included in the study.

    Main outcome measures

    This was the difference between the initial systolic blood pressure (SBP) and the SBP one year later (ABP).

    Secondary criteria were the difference between the initial and final diastolic blood pressure (ADBP) and ABP at two years ; antihypertensive treatment ; stated alcohol consumption (deltaAC) ; deltaGGT ; and body mass index (ABMI).


    The decrease in SBP levels was significantly larger in the intervention group than in the control group : at one year, ASBP values were - 11.9 (15.6) mmHg and - 4.6 (13.8) respectively (p<0.05).

    This benefit was still observed after two years of follow up (-13.8 (17.4) mmHg v - 7.5 (14.2) mmHg (p<0.05)). No difference was observed in DBP.

    The percentage of treated subjects did not differ between gr...

    Mots-clés Pascal : Alcoolisme, Hypertension artérielle, Surveillance, Pression sanguine, Hémodynamique, Homme, Lieu travail, Prévention, France, Europe, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Alcoholism, Hypertension, Surveillance, Blood pressure, Hemodynamics, Human, Work place, Prevention, France, Europe, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0064833

    Code Inist : 002B03F. Création : 199608.