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  1. Quality of life in inflammatory bowel disease.

    Article - En anglais

    The usual indices of activity of Inflammatory Bowel Disease fail to evaluate an important aspect of patients'status, their Quality of Life (QOL).

    A questionnaire dealing with four important aspects of QOL (intestinal and systemic symptoms, emotional and social function) was developed and validated.

    The questionnaire was administered to 72 healthy controls, 57 patients with Ulcerative Colitis and 55 with Crohn's Disease with different disease severity.

    Compared to controls, QOL was impaired not only in the more severe forms of disease, but also in patients in remission.

    In Crohn's Disease, QOL was not closely correlated with the clinical features, thus indicating that the impairment of QOL cannot be inferred from the clinical status and that patients do not « adapt » with the passing of time.

    The questionnaire allows a more comprehensive definition of the patients'state of health, identifying features which might be underestimated as they fail to emerge from the routine clinical evaluation.

    A tool of this kind could be used alongside the activity index of disease, both in clinical studies and during routine follow-up.

    Mots-clés Pascal : Rectocolite ulcérohémorragique, Entérite Crohn, Evaluation, Qualité vie, Questionnaire, Relation incertitude, Symptomatologie, Etude comparative, Homme, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire

    Mots-clés Pascal anglais : Ulcerative colitis, Crohn disease, Evaluation, Quality of life, Questionnaire, Uncertainty relation, Symptomatology, Comparative study, Human, Digestive diseases, Intestinal disease, Inflammatory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0056826

    Code Inist : 002B30A01C. Création : 199608.