Cervical cancer remains an important public health problem, particularly for the urban minority population.
To the authors'knowledge, determinants of cervical cancer survival have not been studied in this high risk population.
This study included all 158 women diagnosed and treated for invasive cervical cancer from January 1,1986, through December 31,1992, at the Grady Memorial Hospital and Clinics (Atlanta, GA).
Medical records were abstracted to determine age at diagnosis, race, International Federation of Gynecology and Obstetrics (FIGO) clinical stage, treatment, and survival.
Pathologic material was reviewed to confirm the diagnosis.
Most patients (80%) were African American, and the stage distribution was similar for African American and white patients.
Sixty-six (42%) had FIGO Stage I disease ; 50%, Stage II or III ; and 8%, Stage IV.
Four-year actuarial survival differed significantly according to clinical stage (Ia=94%, Ib=79%, II=39%, III=26%, IV=0%). Overall survival was lower for patients with glandular carcinomas than for those with squamous cell carcinomas.
This difference was almost entirely due to increased mortality in patients with Stage Ib adenocarcinomas (53% vs. 88% for squamous cell carcinoma, Stage Ib, P=0.03).
The major prognostic markers for cervical cancer survival in this high risk patient population were clinical stage and histology, factors identical to those identified for other populations.
Mots-clés Pascal : Carcinome, Col utérus, Homme, Pronostic, Survie, Epidémiologie, Type histologique, Stade clinique, Race, Milieu urbain, Etats Unis, Amérique du Nord, Amérique, Appareil génital femelle pathologie, Col utérus pathologie, Tumeur maligne, Facteur prédictif
Mots-clés Pascal anglais : Carcinoma, Uterine cervix, Human, Prognosis, Survival, Epidemiology, Histological type, Clinical stage, Race, Urban environment, United States, North America, America, Female genital diseases, Uterine cervix diseases, Malignant tumor, Predictive factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0040802
Code Inist : 002B20C02. Création : 01/03/1996.