We attempted to determine whether elevated levels of the classic coronary heart disease risk factors are associated with increased coronary risk and all-cause mortality among elderly men with and without coronary heart disease at baseline.
The classic coronary risk factor levels and risk of coronary events and total mortality during a 5-year follow-up interval were studied among men aged 65 to 84 years.
Coronary events were fatal myocardial infarction (n=71), any myocardial infarction (n=96) and, among the men without disease, other nonfatal coronary heart disease events (n=80).
Among the 171 men with prevalent coronary heart disease, significant (p<0.05) risk factors for fatal myocardial infarction (n=42) in multivariate analyses were low high density lipoprotein cholesterol (odds ratio [OR] 0.2,95% confidence interval [CI] 0.1 to 0.8 for 1-mmol/liter increase), high ratio of total to high density lipoprotein cholesterol (OR 1.4,95% CI 1.1 to 1.7 for 1-U increase), and smoking more than nine cigarettes daily (OR 6.0,95% CI 1.5 to 24.9 vs. values in men who had never smoked).
The classic risk factors for coronary heart disease appear to be of importance even in old age, especially among men with Drevalent coronarv heart disease.
Mots-clés Pascal : Cardiopathie coronaire, Vieillard, Homme, Facteur risque, Mortalité, Epidémiologie, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Coronary heart disease, Elderly, Human, Risk factor, Mortality, Epidemiology, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0038661
Code Inist : 002B12A03. Création : 01/03/1996.