Lead in tissues of deseased lead smelter workers.
Smelter workers are exposed to a number of metals and other substances in dust, fumes and gases.
The concentrations of lead in liver, lung, kidney, brain, hair and nails were determined in 32 deceased, long-term exposed male lead smelter workers, and compared with those of 10 male controls.
The lead levels in liver, lung, kidney and brain were analyzed by atomic absorption spectrophotometry.
X-ray fluorescence was used for the determinations in hair and nails.
Lead in blood had been determined repeatedly in the lead workers since 1950, which made it possible to calculate a time-integrated blood lead index for each worker.
The highest lead levels in soft tissues were found in liver, followed in order of concentration by kidney, lung and brain, among both exposed workers and controls.
The positive correlation between the lead concentrations in liver and kidney indicates that these organs belong to the same soft tissue lead pool in the body.
In retired lead workers, positive correlations were observed between the lead concentrations in liver and the cumulative blood lead index (CBLI) (rs=0.50 ; p=0.016), as well as between lead levels in kidney and CBLI (rs=0.51 ; p=0.014).
Mots-clés Pascal : Fusion minerai, Travailleur, Plomb, Partie molle, Cheveu, Ongle, Exploration, Toxicité, Homme, Médecine travail
Mots-clés Pascal anglais : Smelting, Worker, Lead, Soft tissue, Hair (head), Nail(anatomy), Exploration, Toxicity, Human, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0021035
Code Inist : 002B03L05. Création : 01/03/1996.