Four hundred and forty-one and 1048 episodes of bacteraemia were prospectively surveyed over a period of 18 months in two hospitals, a 450 bed community hospital and a 900 bed tertiary care urban university hospital.
Incidence of bacteraemia was 2.18 per 1000 hospitalization days (10.1 per 1000 admissions) in the community hospital and 2.64 per 1000 hospitalization days (12.0 per 1000 admissions (P<0.004)) in the university hospital.
Sixty six and 62% of episodes of bacteraemia were community acquired.
The majority of bacteraemic episodes originated on the internal medicine wards of both hospital-46.7% and 58.7% respectively ; the incidence of bacteraemia in the medical divisions of both hospitals was 23.1 and 17.5 per 1000 admissions respectively (P<0.01).
Overall mortality rates were 22% and 26.7% respectively. 39.9% and 44% of all isolates were Gram-positive pathogens.
Escherichia coli was the commonest Gram-negative pathogen in both hospitals, particularly the community hospital-47.5% vs 32.8% (P<0.005) of all Gram-negative pathogens, while Pseudomonas spp. were significantly more common in the university hospital-18.5% vs 11.8% (P<0.02).
Non-enterococcal streptococci were more common in the community hospital while enterococci were far more common at the university hospital-15.1% vs 1% of all Gram-positive pathogens (P<0.05).
A high resistance rate to ofloxacin was found at the university hospital among.
Mots-clés Pascal : Bactériémie, Centre hospitalier universitaire, Epidémiologie, Etude comparative, Hôpital général, Antibiotique, Antibactérien, Sensibilité résistance, Bactériose, Infection
Mots-clés Pascal anglais : Bacteremia, Teaching hospital, Epidemiology, Comparative study, General hospital, Antibiotic, Antibacterial agent, Sensitivity resistance, Bacteriosis, Infection
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0014007
Code Inist : 002B30A01A2. Création : 01/03/1996.