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  1. Genetic services for familial cancer patients : a survey of National Cancer Institute Cancer Centers.

    Article - En anglais

    In the past decade, significant progress has been made in understanding the genetic component of familial cancers.

    Genes associated with familial colon and breast cancers have recently been isolated and molecular diagnostic tests are expected to become available in the near future.

    Clinicians now have the opportunity to recognize and counsel individuals with elevated risk of cancer by identifying risk factors and genes associated with cancer predisposition.

    The rapid advances in molecular technology are a direct challenge to the medical community and cancer centers to supply specialized clinical services for familial cancers.

    We sought to ascertain the activities of cancer centers in the development of programs and the provision of genetic services for familial cancer.

    We surveyed 41 centers with National Cancer Institute (NCI) cancer center support grants.

    One half of the centers responding (17 of 34) reported that they provide some genetic services for familial cancer.

    About one half of these 17 centers (eight [57% ] of 14 ; the three remaining clinics that responded had incomplete information on this indicator) see a variety of patient types on a small scale (fewer than 100 patients per year), and most provide four basic clinical evaluations : medical evaluation, cancer risk assessment, genetic counseling, and pedigree analysis.

    Staffing of each center varied widely, as did the types of screening services offered (including molecular diagnostic testing).

    Mots-clés Pascal : Tumeur maligne, Dépistage, Diagnostic, Facteur risque, Analyse risque, Etude familiale, Conseil génétique, Institution spécialisée, Enquête, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Malignant tumor, Medical screening, Diagnosis, Risk factor, Risk analysis, Family study, Genetic counseling, Specialized institution, Inquiry, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0007339

    Code Inist : 002B04B. Création : 01/03/1996.