To determine the immunity to hepatitis B, poliomyelitis and measles in fully vaccinated Aboriginal and Torres Strait Island children in north Queensland.
A cross-sectional survey of immunity in a sample of children ; 101 fully vaccinated Aboriginal and Torres Strait Island children, with a median age of 24.5 months, from 10 communities in North Queensland participated in this study.
The main outcome measures were the prevalence of adequate antibody levels against hepatitis B, poliomyelitis and measles.
Only 54% (95% Cl 44-63%) of the children had adequate immunity (=10 m iu/mL) to hepatitis B, and one child had been infected despite vaccination.
Although all the children (95% Cl 96-100%) had adequate immunity (i.e. neutralizing antibodies at a dilution of =1 : 8) to poliovirus 2, only 93% (95% Cl 86-96%) and 60% (95% Cl 50-69%) had adequate immunity to polioviruses 1 and 3, respectively.
Although a relatively low proportion of the children had adequate antibody levels against hepatitis B the clinical significance of this observation is uncertain.
Further studies are needed to determine whether fully vaccinated Torres Strait Island children have been adequately protected and whether they require a booster dose of hepatitis B vaccine.
A substantial proportion of fully vaccinated Aboriginal and Torres Strait Island children are inadequately protected against poliomyelitis.
Mots-clés Pascal : Appareil digestif pathologie, Foie pathologie, Système nerveux pathologie, Moelle épinière pathologie, Prévention, Enfant, Homme, Vaccination, Immunoprotection, Aborigène, Hépatite virale B, Virose, Infection, Rougeole, Poliomyélite antérieure, Système nerveux central pathologie, Australie, Océanie
Mots-clés Pascal anglais : Digestive diseases, Hepatic disease, Nervous system diseases, Spinal cord disease, Prevention, Child, Human, Vaccination, Immunoprotection, Aboriginal, Viral hepatitis B, Viral disease, Infection, Measles, Acute anterior poliomyelitis, Central nervous system disease, Australia, Oceania
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0001006
Code Inist : 002B05A02. Création : 01/03/1996.