New Zealand soils are deficient in the essential micronutrient, selenium.
New Zealand infants have low selenium levels at birth and experience a further decline if fed cows milk based formula.
This study examined the selenium status of infants fed with a new commercially available selenium supplemented formula.
Forty-four newborn infants, whose mothers wished to formula feed, were randomized in an open controlled trial to be fed a commercially available selenium supplemented cows milk formula (containing 17 mug Se/L) or an unsupplemented formula (containing 4.6 mug Se/L).
Cord, 1 and 3 month blood samples were obtained for selenium status (plasma and red cell selenium and glutathione peroxidase) and thyroid function.
Mean plasma selenium and glutathione peroxidase values were significantly higher in supplemented than unsupplemented infants at 1 month and 3 months.
Analysis within treatment groups between time points showed that selenium supplementation prevented the fall in plasma selenium from birth to 1 month seen in unsupplemented infants and was associated with a rise in levels between 1 and 3 months (P=0.002).
Supplementing cows milk formula with selenium to replicate the levels found in breast milk is nutritionally sound.
Feeding from a few days of age with a formula containing 17 mug Se/L in infants with low selenium status at birth is sufficient to cause a rise to 80% of adult levels at 3 months of age.
Mots-clés Pascal : Exploration, Nouveau né, Etude comparative, Sélénium, Oligoélément, Nutrition, Dosage, Nouvelle Zélande, Lait infantile, Supplémentation, Alimentation, Homme, Océanie
Mots-clés Pascal anglais : Exploration, Newborn, Comparative study, Selenium, Trace element (nutrient), Nutrition, Assay, New Zealand, Infant formula, Supplementation, Feeding, Human, Oceania
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0001005
Code Inist : 002B30A01A2. Création : 01/03/1996.