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  1. The need to consider survival, outcome, and expense when evaluating and treating patients with unknown primary carcinoma.

    Article - En anglais


    Patients who present with unknown primary carcinomas represent 10% to 15% of the patients with cancer who present to medical centers.

    Despite data in the literature indicating minimal success in determining the location of primary carcinomas, these patients continue to be evaluated exhaustively.

    Additionally, identification of the location of primary carcinomas does not often affect treatment.

    Clinical treatment and prognosis are only affected if a reevaluation of the pathologic findings yields a potentially curative diagnosis of an undifferentiated lymphoma, germ cell tumor, or a hormonally sensitive carcinoma.


    Tumor registry files from January 1,1990, through December 31,1992, were retrospectively retrieved to identify adult patients who presented with metastasis of an unknown primary site at the H. Lee Moffitt Cancer Center and Research Institute, a 162-bed tertiary care cancer center specialty hospital affiliated with the University of South Florida College of Medicine, Tampa.

    Medical records were reviewed for age, sex, histologic findings of previous malignant growth, types and duration of symptoms, and mode of presentation.

    Fifty-six of the 199 patients were included in the study ; 31 were men (55.4%) and 25 were women (44.6%), with ages ranging from 33 to 83 years.

    Diagnostic evaluations were reviewed and included data from procedures conducted at both the H. Lee Moffitt Cancer Center and at outside facilities.

    Mots-clés Pascal : Epithélioma, Primaire, Survie, Evolution, Economie santé, Recherche, Origine, Bilan santé, Attitude, Homme, Tumeur maligne

    Mots-clés Pascal anglais : Carcinoma, Primary, Survival, Evolution, Health economy, Research, Origin, Medical check up, Attitude, Human, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0591703

    Code Inist : 002B30A01A2. Création : 01/03/1996.