To identify different subsets of patients from a large tertiary care center who were presumptively referred for and/or diagnosed with systemic lupus erythematosus (SLE) (or followed up).
All patients who were referred, followed up, and/or diagnosed with SLE at our center, who had disease duration of ¾5 years, and who resided in Alabama, were identified and their charts reviewed and abstracted.
Abstracted data were reviewed by 3 rheumatologists, and patients were assigned to 1 of 3 categories : 1) SLE by the American College of Rheumatology (ACR ; formerly, the American Rheumatism Association) criteria, 2) clinical SLE but not meeting 4 of the ACR criteria, or 3) fibromyalgia-like manifestations with antinuclear antibody (ANA) positivity.
There were 90 patients in the first group (criteria), 22 in the second group (clinical), and 37 in the third group (fibromyalgia-like).
Patients in all 3 groups were predominantly women.
Only 5% of the fibromyalgia-like group were African-American, compared with 55-65% for the other 2 groups.
Organ system involvement occurred with comparable frequency in the first 2 groups, but mucocutaneous and hematologic abnormalities were more frequent in the criteria group ; in contrast, the patients with fibromyalgia-like symptoms primarily presented with arthralgias/myalgias, fatigue, depression, and sleep disturbances, as well as mucocutaneous manifestations.
Mots-clés Pascal : Lupus érythémateux, Disséminé, Homme, Symptomatologie, Diagnostic, Critère, Milieu hospitalier, Epidémiologie, Recrutement, Peau pathologie, Tissu conjonctif pathologie, Maladie système, Maladie autoimmune, Immunopathologie
Mots-clés Pascal anglais : Lupus erythematosus, Disseminated, Human, Symptomatology, Diagnosis, Criterion, Hospital environment, Epidemiology, Recruitment, Skin disease, Connective tissue disease, Systemic disease, Autoimmune disease, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0590074
Code Inist : 002B07. Création : 01/03/1996.