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  1. Biologic sex as a risk factor for Helicobacter pylori infection in healthy young adults.

    Article - En anglais

    Diseases associated with Helicobacter pylori infection, such as peptic ulcer disease and gastric cancer, afflict men more frequently than women.

    No study, however, has demonstrated any difference in sex-specific rates of H. pylori infection.

    In a healthy population undergoing multiphasic health evaluations in 1992-1993 as members of the Kaiser Permanente Medical Care Program of Northern California, adults aged 20-39 years were screened for antibodies to H. pylori infection using a serum enzyme-linked immunosorbent assay and were surveyed with regard to their demographic characteristics and health practices.

    Men consistently had a higher prevalence of antibodies across all strata of race/ethnicity, age, education, and income, and in multivariate analysis male sex remained significantly associated with infection (odds ratio=2.0,95% confidence interval 1.2-3.1).

    African-American race, Hispanic ethnicity, increasing age, lower levels of education, and birth in a developing country were also associated with infection in multivariate analysis.

    Data from previously reported seroprevalence studies support a tendency for men to have a higher risk of infection.

    The higher prevalence of infection among young males as observed in Northern California may account in part for the increased incidence of H. pylori-related diseases among men in later decades of life.

    Mots-clés Pascal : Bactériose, Infection, Estomac, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Epidémiologie, Sexe, Adulte jeune, Homme, Sérologie, Ethnie, Californie, Etats Unis, Amérique du Nord, Amérique, Estomac pathologie, Appareil digestif pathologie

    Mots-clés Pascal anglais : Bacteriosis, Infection, Stomach, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Epidemiology, Sex, Young adult, Human, Serology, Ethnic group, California, United States, North America, America, Gastric disease, Digestive diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0580379

    Code Inist : 002B05B02F. Création : 01/03/1996.