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  1. A community trial of the impact of improved sexually transmitted disease treatment on the HIV epidemic in rural Tanzania. II : Baseline survey results.

    Article - En anglais

    Objectives 

    To determine baseline HIV prevalence in a trial of improved sexually transmitted disease (STD) treatment, and to investigate risk factors for HIV.

    To assess comparability of intervention and comparison communities with respect to HIV/STD prevalence and risk factors.

    To assess adequacy of sample size.

    Setting 

    Twelve communities in Mwanza Region, Tanzania.

    Methods 

    Approximately 1000 adults aged 15-54 years were randomly sampled from each community.

    Subjects were interviewed, and HIV and syphilis serology performed.

    Men with a positive leucocyte esterase dipstick test on urine, or reporting a current STD, were tested for urethral infections.

    Results 

    A total of 12 534 adults were enrolled.

    Baseline HIV prevalences were 7.7% (roadside), 3.8% (rural) and 1.8% (islands).

    Associations were observed with marital status, injections, education, travel, history of STD and syphilis serology.

    Prevalence was higher in circumcized men, but not significantly after adjusting for confounders.

    Intervention and comparison communities were similar in the prevalence of HIV (3.8 versus 4.4%), active syphilis (8.7 versus 8.2%), and most recorded risk factors.

    Within-pair variability in HIV prevalence was close to the value assumed for sample size calculations.

    Conclusions 

    The trial cohort was successfully established.

    Comparability of intervention and comparison communities at baseline was confirmed for most factors.

    Mots-clés Pascal : Maladie sexuellement transmissible, Epidémie, Zone rurale, SIDA, Virose, Infection, Homme, Epidémiologie, Tanzanie, Afrique, Facteur risque, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Sexually transmitted disease, Epidemic, Rural area, AIDS, Viral disease, Infection, Human, Epidemiology, Tanzania, Africa, Risk factor, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0577171

    Code Inist : 002B06D01. Création : 01/03/1996.