Objectives The present study was undertaken to examine the relation between visual functions and occupational exposure to styrene.
Methods A total of 128 workers (85% of the total population), from three glass-reinforced plastics plants in Canada, agreed to participate in the study.
Environmental and biological measures were made on the day (s) prior to the assessment of near visual acuity (National Optical Visual Chart), chromatic discrimination (Lanthony D-15 desaturated panel), and near contrast sensitivity (Vistech 6000).
The analyses were performed on 81 workers with near visual acuity of at least 1 min of arc at 0.5 m. Results The subjects were relatively young [29 (SD 8) years], with little seniority [5 (SD 4) years]. Styrene exposure for 8 h ranged from 6 to 937 (first quartile 21 mg. m-3, third quartile 303 mg. m-3), depending on the job site.
The end-shift concentrations of urinary mandelic acid ranged from nondetectable to 1.90 mmol. mmol creatinine-1, Significant positive relations were found between the internal and external styrene exposure measurements and color vision loss adjusted for age, alcohol consumption, and seniority in a multiple regression analysis.
Conclusions These findings suggest that there is a positive relation between styrene exposure and early color and contrast vision dysfunction.
Mots-clés Pascal : Styrène, Solvant organique, Toxicité, Exposition professionnelle, Médecine travail, Homme, Oeil pathologie, Trouble vision, Vision couleur, Contraste, Epidémiologie, Canada, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Styrene, Organic solvent, Toxicity, Occupational exposure, Occupational medicine, Human, Eye disease, Vision disorder, Color vision, Contrast, Epidemiology, Canada, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0565871
Code Inist : 002B03L04. Création : 01/03/1996.