Poor survival among African American patients with breast cancer has been attributed to low socioeconomic status and lack of access to health care.
However, Hispanics of equivalent socioeconomic status and health care access exhibit much higher survival rates, almost comparable to whites.
This suggests that biologic differences play a role in differences in breast cancer survival in addition to socioeconomic and health care access factors.
The authors studied clinical and molecular differences between patients with breast cancer of different ethnicity to determine biologic explanations for the observed differences in survival.
Consecutive patients scheduled for breast biopsies were identified preoperatively and were interviewed.
Whites and Hispanics were significantly older at menopause.
The molecular indices associated with breast cancer prognosis do not differ significantly among whites, African Americans, and Hispanics, suggesting that the reported differences in survival among these groups are not due to biologic differences in breast cancer among ethnic groups.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Pronostic, Epidémiologie, Homme, Femelle, Ethnie, Noir américain, Caucasoïde, Etats Unis, Amérique du Nord, Amérique, Etude comparative, Négroïde, Glande mammaire pathologie, Hispanoaméricain
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Prognosis, Epidemiology, Human, Female, Ethnic group, Black American, Caucasoid, United States, North America, America, Comparative study, Negroid, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0508267
Code Inist : 002B20E02. Création : 01/03/1996.