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  1. Stable human T-lymphotropic virus type I carrier rates for 7 years among a teenaged blood donor cohort of 1986 in Kumamoto, Japan.

    Article - En anglais

    The human T-lymphotropic virus type I (HTLV-I) carrier rates for blood donors in Kumamoto, Kyushu, Japan for 8 years, 1986-1993, are currently available.

    The data show that 16-19-year-olds in 1986 and 20-29-year-olds in 1993 represent nearly the same cohort, because the median age in both groups is 24.5 years in 1993.

    Therefore, comparison of the HTLV-I positive rate for the two groups gives an estimate of the change in the rate over 7 years within the cohort.

    In males, 265 of 22,143 donors (1.20%) were seropositive for HTLV-I among 16-19-year-olds in 1986, and 214 were seropositive among 20,076 (1.07%) donors in 20-29-year-olds in 1993.

    In females, 203 were seropositive among 20,677 (0.98%) donors in 16-19-year-olds in 1986, and 154 were seropositive among 18,660 (0.83%) donors in 20-29-year-olds in 1993.

    Thus, the seropositive rates declined in both sexes.

    However, the average annual rate of immigration to Kumamoto Prefecture was 2.37%. If seropositive rates for 20-29-year-olds in 1993 are adjusted for the dilution effect due to immigration (under the assumption that all immigrants were HTLV-I negative), the adjusted carrier rate for males is 1.26% and that for females is 0.98%. The adjusted carrier rates for both sexes are almost the same as those for 16-19-year-olds in 1986.

    This indicates that horizontal transmission was negligible for those in the cohort who were in their early reproductive period.

    Mots-clés Pascal : Virose, Infection, Virus HTLV1, Retroviridae, Virus, Séropositivité, Donneur sang, Taux, Etude cohorte, Epidémiologie, Japon, Asie, Adolescent, Homme

    Mots-clés Pascal anglais : Viral disease, Infection, HTLV-I virus, Retroviridae, Virus, Seropositivity, Blood donor, Rate, Cohort study, Epidemiology, Japan, Asia, Adolescent, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0487783

    Code Inist : 002B05C02D. Création : 01/03/1996.