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  1. Clusters of acute appendicitis : further evidence for an infectious aetiology.

    Article - En anglais

    Andersson R (Department of Surgery, Ryhov Hospital, S-551 85, Jönköping, Sweden), Hugander A, Thulin A, Nyström P O and Olaison G. Clusters of acute appendicitis : Further evidence for an infectious aetiology.

    International Journal of Epidemiology 1995 ; 24 : 829-833.


    The aetiology of appendicitis, the commonest cause of acute abdomen, is unknown.

    Infection has been proposed but the evidence has been unconvincing.

    The purpose of the present study was to investigate if temporo-spatial clustering and outbreaks, characteristics of infectious diseases, could be found in appendicitis cases in a defined Swedish population.


    Temporo-spatial clustering among 1155 cases from three districts of Jönköping County in 1984-1990 was identified by Knox space-time cluster analysis.

    Outbreaks were identified by retrospective study of temporal variations in 3590 consecutive cases of acute appendicitis from the city of Jönköping in 1969-1990.


    Space-time clustering was found among patients with operations less than 60 days apart (observed/expected [O/E]-ratio 1.46, P=0.016).

    The finding of temporo-spatial interaction and outbreaks among appendicitis cases supports the concept that appendicitis may be caused by infectious agents.

    Mots-clés Pascal : Appendicite, Epidémiologie, Analyse amas, Etiologie, Homme, Analyse temporelle, Analyse spatiale, Foyer infectieux, Suède, Europe, Appareil digestif pathologie, Intestin pathologie

    Mots-clés Pascal anglais : Appendicitis, Epidemiology, Cluster analysis, Etiology, Human, Time analysis, Spatial analysis, Infectious focus, Sweden, Europe, Digestive diseases, Intestinal disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0474521

    Code Inist : 002B13B03. Création : 01/03/1996.