The role of diet as a risk factor for osteoporotic fractures is unclear.
In two counties in central Sweden we investigated the association between dietary intake and the risk of proximal femoral fractures in a case-control study nested in a cohort.
Women born in 1914-1948 were asked to fill out a food frequency questionnaire when invited to attend for mammographic screening between the years 1987 and 1990.
More than 65 000 women completed the questionnaire.
Those who had participated in the enquiry and subsequently sustained a first hip fracture were defined as cases.
When highest quartile of intake was compared to lowest, intakes of iron (adjusted odds ratio [OR] of 3.3,95% confidence interval [Cl] : 1.6-6.9), magnesium (adjusted OR=2.7,95% Cl : 1.3-6.0) and vitamin C (adjusted OR=1.9,95% Cl : 1.2-3.1) were found to be independent risk factors for hip fracture.
High calcium intake did not protect against hip fracture.
Smoking, low physical activity in leisure time, low body mass index, earlier fracture of the distal forearm and diabetes were all risk factors while postmenopausal hormone replacement therapy protected against hip fracture.
This large study indicates new dietary risk factors for hip fracture.
The association between high dietary intake of iron, magnesium and vitamin C and risk of hip fracture has not been reported previously.
Mots-clés Pascal : Fracture, Fémur, Proximal, Col fémoral, Epidémiologie, Homme, Femelle, Alimentation, Régime alimentaire, Facteur risque, Suède, Europe, Système ostéoarticulaire pathologie, Traumatisme
Mots-clés Pascal anglais : Fracture, Femur, Proximal, Femoral neck, Epidemiology, Human, Female, Feeding, Diet, Risk factor, Sweden, Europe, Diseases of the osteoarticular system, Trauma
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0473283
Code Inist : 002B16H. Création : 01/03/1996.