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  1. High alcohol intake as a risk and prognostic factor for community-acquired pneumonia.

    Article - En anglais

    Objective 

    To evaluate whether high alcohol intake is an independent risk factor for community-acquired pneumonia in middle-aged people and whether it confers a poor prognosis.

    Methods 

    A two-phase study was performed.

    Risk factors for community-acquired pneumonia were evaluated in a case-control study of 50 patients and 50 controls.

    Prognostic factors and microbiologic and clinical features were then evaluated in a cohort study of the 50 middle-aged patients with community-acquired pneumonia.

    Results 

    In the first study, the only independent risk factor for community-acquired pneumonia was high alcohol intake (P<. 02).

    In the second study, patients with chronic alcoholism had a higher incidence of pneumonia caused by gram-negative bacilli (P<. 03), as well as a higher incidence of Candida albicans (P<. 03), Staphylococcus aureus (P<. 0001), and gram-negative bacilli (P<. 001) in the cultures of pharyngeal smears than did the nonalcoholics.

    Compared with nonalcoholic patients, alcoholic patients with pneumonia showed more severe clinical symptoms (P<. 02), required longer intravenous treatment (P<. 02) and longer hospital stay (P<. 01), and had multilobar involvement and pleural effusion (both P<. 01), as well as slower resolution of pulmonary infiltrates.

    The only prognostic factor for mortality was high alcohol intake (P<. 03).

    Conclusions 

    High alcohol intake is the main risk factor for developing community-acquired pneumonia in middle-aged people.

    Mots-clés Pascal : Alcoolisme, Facteur risque, Pneumonie, Bactériose, Infection, Pronostic, Epidémiologie, Homme

    Mots-clés Pascal anglais : Alcoholism, Risk factor, Pneumonia, Bacteriosis, Infection, Prognosis, Epidemiology, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0470485

    Code Inist : 002B05B02E. Création : 01/03/1996.