Our goal was to address the issues listed above with a large case-control study.
We conducted a population-based case-control study in Maine, Massachusetts (excluding the four counties that include metropolitan Boston), New Hampshire, and Wisconsin.
Case patients were eligible if their diagnosis of invasive breast cancer was first reported to one of the four statewide cancer registries during the period of 1988 through 1991.
During the accrual period, 11 879 potentially eligible case patients and 16217 control subjects were identified.
After excluding ineligible women from the study, telephone interviews were obtained from 6888 case patients and 9424 control subjects.
Lifetime average alcohol consumption (measured as the average grams per day consumed from age 16 to the recent past) and recent alcohol consumption (average grams per day consumed in the previous age interval) were associated with risk of developing breast cancer.
In these data, alcohol consumption was clearly related to breast cancer risk.
Risk appeared to increase even at moderate levels of consumption.
For women of all ages combined, consumption before 30 years of age was not an important determinant of risk. [J Natl Cancer Inst 87 : 923-929,1995].
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Epidémiologie, Alcoolisme, Massachusetts, Etats Unis, Amérique du Nord, Amérique, Homme, Glande mammaire pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Epidemiology, Alcoholism, Massachusetts, United States, North America, America, Human, Mammary gland diseases, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0459649
Code Inist : 002B20E02. Création : 01/03/1996.