Objectives-To study the presentation and survival of patients who present with their first diagnosis of being HIV positive at the same time as their AIDS defining illness.
Design-Retrospective study of patients presenting with AIDS between 1991 and 1993.
Main outcome measures-AIDS defining illness at presentation and survival after diagnosis of AIDS.
Between January 1991 and December 1993,97 out of 436 patients (22%) presented with their first AIDS defining illness coincident with their first positive result of an HIV test (group B).
The remaining 339 patients (78%) had tested positive for HIV-1 infection within the previous eight years and had consequently been followed up in clinics before developing their first AIDS defining illness (group A).
The two groups of patients did not differ in age and sex distribution, risk factors for HIV-1 infection, nationality, country of origin, or haematological variables determined at the time of the AIDS defining illness.
Conclusions-Subjects who are HIV positive and present late are a challenge to the control of the spread of HIV infection because they progress from asymptomatic HIV infection to AIDS without receiving health care.
The finding that presentation with an AIDS defining illness coincident with a positive result in an HIV test did not have a detrimental effect on survival gives insights into the effects of medical intervention on disease progression after a diagnosis of AIDS.
Mots-clés Pascal : Immunopathologie, SIDA, Virose, Infection, Epidémiologie, Homme, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Séropositivité, Simultané, Angleterre, Grande Bretagne, Royaume Uni, Europe
Mots-clés Pascal anglais : Immunopathology, AIDS, Viral disease, Infection, Epidemiology, Human, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Seropositivity, Concurrent, England, Great Britain, United Kingdom, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0446801
Code Inist : 002B06D01. Création : 01/03/1996.