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  1. Prevalence of hepatitis B virus (HBV) infection in Singapore men with sexually transmitted diseases and HIV infection : role of sexual transmission in a city with intermediate HBV endemicity.

    Article - En anglais

    Study objectives

    To describe the prevalence of hepatitis B virus (HBV) infection in patients with sexually transmitted diseases (STD) and human immunodeficiency virus (HIV) infection, and to determine the role of sexual transmission of HBV infection in Singapore.

    Design

    A cross sectional study of all consecutive men presenting with a new episode ofSTD at a government outpatient clinic and all men with HIV infection on routine follow up at a government hospital.

    The prevalence of various HBV markers was compared with that of healthy males aged 15 years and above (controls).

    Setting

    Singapore, a city state of intermediate HBV endemicity.

    Subjects

    These comprised 497 STD patients, 47 HIV infected patients, and 418 controls.

    Main results

    The overall seroprevalences of HBV infection in STD patients, HIV infected patients, and control subjects were 41.2%, 61.7%, and 33.3%, respectively (p<0.001).

    The seroprevalences of hepatitis B surface antigen (6.2%, 8.5%, and 4.5%, respectively) were comparable in the three groups.

    Conclusion

    The importance of sexual transmission of HBV in an area of intermediate HBV endemicity was confirmed.

    Patients attending STD clinics should be routinely screened for HBV markers and those found to be seronegative should be strongly advised to be immunised against this virus.

    Mots-clés Pascal : Hépatite virale B, Virose, Infection, Epidémiologie, Prévalence, SIDA, Maladie sexuellement transmissible, Association, Sérologie, Homme, Singapour, Asie, Sexualité, Transmission homme homme, Appareil digestif pathologie, Foie pathologie, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Epidemiology, Prevalence, AIDS, Sexually transmitted disease, Association, Serology, Human, Singapore, Asia, Sexuality, Transmission from man to man, Digestive diseases, Hepatic disease, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0424574

    Code Inist : 002B05C02G. Création : 01/03/1996.