International symposium on human health and environment. Salsomaggiore Terme (Parma) ITA, 1994/09/25.
The relationship between blood lead (B-Pb) indices and bone lead was determined in 81 smelter workers.
Lead exposure had changed dramatically since the smelter opened 27 years ago ; therefore, workers were stratified by years employed.
Seventy workers, hired prior to 1979 (Group 1), had a mean (range) age of 46 years (35-64), mean years of employment 23 (16-27), mean years of education 8 (0-13), mean B-Pb 26 mug dl-1 (13-43), mean time-weighted average (TWA) B-Pb 44 mug dl-1 (23-57) and mean integrated blood lead index (IBL), 983 mug Pb year dl-1 (537-1437).
Eleven workers, hired after 1978 (Group 2), had a mean age of 34 years (24-55), mean years of employment 11 (5-14), mean years of education 11 (8-12), mean B-Pb 26 mug dl-1 (8-13), mean TWA 33 mug dl-1 (17-44) and mean IBL 378 mug year dl-1 (81-555).
Bone lead measured in the mid-tibia used K-X-ray fluorescence.
Mean bone lead in Group 1 and Group 2 was 45 (-7-90) and 11 (-12-33) mug Pb (g bone mineral) - 1, respectively.
Linear regression analysis demonstrated a significant relationship between bone lead and B-Pb indices.
B-Pb accounted for 10.8%, years employed 12.7%, TWA 31.4% and IBL 36% of the bone lead variance.
Using a previously established relationship, the mean bone lead predicted a mean B-Pb content of approximately 8 mug dl-1 in Group I as compared to 2 mug dl-1 in Group 2. The mean B-Pb was 26 mug dl-1 in both groups despite differences in contribution from bone stores.
Mots-clés Pascal : Plomb, Métal lourd, Exposition professionnelle, Fonderie, Industrie métallurgique, Homme, Surveillance biologique, Os, Sang, Médecine travail
Mots-clés Pascal anglais : Lead, Heavy metal, Occupational exposure, Foundry, Metallurgical industry, Human, Biological monitoring, Bone, Blood, Occupational medicine
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0412372
Code Inist : 002B03L05. Création : 01/03/1996.