Bloodstream infections associated with a needleless intravenous infusion system in patients receiving home infusion therapy.
- To determine risk factors for bloodstream infections (BSls) in an outbreak among patients receiving home intravenous infusion therapy.
Case-control and retrospective cohort studies.
- Home health agency.
- Patients receiving home intravenous infusion therapy from Rhode Island Home Therapeutics (RIHT) from January through December 1993.
Main Outcome Measure
- Development of primary BSI.
- We compared patients with BSI (ie, case patients) with randomly selected noninfected RIHT patients receiving intravenous therapy, conducted a cohort study of all RIHT patients receiving intravenous therapy via a central venous catheter (CVC), and conducted a culture survey of injection cap luminal fluid.
- Case patients were more likely than controls to have had therapy via a CVC (11/11 vs 14/32 ; odds ratio [OR] undefined ; P<. 001) or total parenteral nutrition and intralipid therapy (TPN/IL) (9/11 vs 3/32 ; OR, 43.5 ; 95% confidence interval [Cl], 4.9 to 510.0).
Among RIHT patients with CVCs, risk factors for BSI were receipt of TPN/IL (9/35 vs 2/67 ; rate ratio [RR], 8.6 ; 95% Cl, 2.0 to 37.7) or use of a needleless infusion system.
Only the combination of both exposures was significantly associated with development of a BSI (P<. 001).
- Our data suggest that a needleless device used for TPN/IL was associated with increased risk of BSI when injection caps were changed every 7 days.
Mots-clés Pascal : Facteur risque, Infection, Iatrogène, Chimiothérapie, A domicile, Perfusion, Voie intraveineuse, Homme
Mots-clés Pascal anglais : Risk factor, Infection, Iatrogenic, Chemotherapy, At home, Perfusion, Intravenous administration, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0411864
Code Inist : 002B27B14B. Création : 01/03/1996.