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  1. Combined registry for the clinical use of mechanical ventricular assist pumps and the total artificial heart in conjunction with heart transplantation : sixth official report-1994.

    Article - En anglais

    Background 

    The Combined Registry has existed since 1985 with a design toward the voluntary submission of data from centers undertaking mechanical circulatory assistance.

    Methods 

    The compiled results of the Combined Registry for the Clinical Use of Mechanical Ventricular Assist Pumps and the Total Artificial Heart was reviewed and subjected to strict statistical evaluation.

    Results 

    More than 2000 implanted devices have been reported through January 1994, and 584 of these have been placed with the intention of bridge to heart transplantation.

    Nearly 70% of these patients have subsequently undergone heart transplantation, and 69% of those patients have survived to discharge from the hospital.

    Outcome statistics continue to favor isolated left ventricular support, although only discharge rates are significantly improved over right (p=0.01) or biventricular assistance (p<0.001) and the total artificial heart (p<0.001).

    Within the group of left ventricular devices no individual mode of support proved advantageous over the others for transplantation or discharge rates.

    Conclusions 

    These data show the continued success with these devices for bridging critically ill patients to transplantation.

    Additionally, it supports the ongoing development of devices implanted for long-term use, which might replace orthotopic transplantation for those patients currently deemed marginal candidates.

    J HEART LUNG TRANSPLANT 1995 ; 14 : 585-93.

    Mots-clés Pascal : Coeur artificiel, Homme, Ventricule artificiel, Epidémiologie, Assistance cardiocirculatoire

    Mots-clés Pascal anglais : Artificial heart, Human, Artificial ventricle, Epidemiology, Cardiocirculatory assistance

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0408452

    Code Inist : 002B27B01. Création : 01/03/1996.