Pure testicular teratoma in adults is a relatively rare malignant tumor with the ability to invade and metastasize.
Pure teratoma generally is believed to be less aggressive and less likely to progress, to present in lower stages, and to have better survival rates then other forms of germ cell tumor.
Consequently, clinical stage A patients with pure testicular teratoma commonly have been considered to be managed best by surveillance.
A computerized database search identified 41 patients presenting to Indian University with pure teratoma in the orchiectomy specimen.
The experience with these patients was reviewed.
The overall risk of lymph node metastasis in retroperitoneal lymph node dissection (RPLND) and the risk of relapse after RPLND for patients with low stage pure testicular teratoma (groups I-III) were 40 and 16%, respectively.
In patients with clinical Stage A teratoma, the risk of retroperitoneal metastasis in RPLND was 16.7% and the relapse rate was 11.1%. Conclusions.
These data provide additional confirmation of the metastatic potential of pure testicular teratoma.
The proper management of the adult clinical stage A patient with primary pure teratoma of the testis should not necessarily differ from the management of any other histologic type of nonseminomatous testicular tumor.
Accordingly, histologic diagnosis of pure teratoma should not mandate surveillance.
Cancer 1995 ; 75 : 2244-50.
Mots-clés Pascal : Tératome malin, Testicule, Adulte, Homme, Potentiel, Métastatique, Pronostic, Histopathologie, Stade clinique, Epidémiologie, Indiana, Etats Unis, Amérique du Nord, Amérique, Appareil génital mâle pathologie, Testicule pathologie, Tumeur maligne
Mots-clés Pascal anglais : Malignant teratoma, Testicle, Adult, Human, Potential, Metastatic, Prognosis, Histopathology, Clinical stage, Epidemiology, Indiana, United States, North America, America, Male genital diseases, Testicular diseases, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0398850
Code Inist : 002B20B02. Création : 01/03/1996.