Although the effects of cigarette smoking on cancer risk have been well documented, there remain several outstanding issues to be clarified, including the determination of which types of cancer are associated with smoking and estimation of the magnitude of the effect of smoking on different types of cancer.
A further issue is whether the effects seen elsewhere can be demonstrated in Canada, where tobacco products differ somewhat from those in other countries.
A case-control study was undertaken in Montreal to investigate the associations between a large number of environmental and occupational exposures on the one hand, and several types of cancer on the other.
Between 1979 and 1985, interviews were carried out with incident male cases of 21 types of cancer, including 15 anatomical sites and six histological subtypes.
The interview was designed to obtain detailed information on smoking histories, job histories, and other potential confounders.
Altogether, 3730 cancer patients and 533 population controls were interviewed.
For each type of cancer analysed, two control groups were used.
Of the 21 types of cancer examined, the following were associated with smoking among men in Montreal : lung (including all major histological subtypes), bladder (and its main histological subtypes), oesophagus, stomach and pancreas.
Smoking likely accounts for a large proportion of cancers occurring at these sites.
Mots-clés Pascal : Tumeur maligne, Epidémiologie, Tabagisme, Homme, Etude multicentrique, Québec, Canada, Amérique du Nord, Amérique, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Epidemiology, Tobacco smoking, Human, Multicenter study, Quebec, Canada, North America, America, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0365591
Code Inist : 002B03E. Création : 01/03/1996.