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  1. Nosocomial bloodstream infections : secular trends in rates, mortality, and contribution to total hospital deaths.

    Article - En anglais

    Background 

    Nosocomial bloodstream infections occur at a rate of 1.3 to 14.5 per 1000 hospital admissions and are believed to lead directly to 62 500 deaths per year in the United States.

    Measures of the incidence and the proportion of all hospital deaths related to deaths from these infections provide estimates of their impact.

    Methods 

    A 12-year retrospective study using prospectively collected data from a hospital-wide surveillance system for nosocomial infections in a 900-bed tertiary care institution.

    Results 

    Between 1980 and 1992, a total of 3077 patients developed 3464 episodes of nosocomial bloodstream infection.

    The crude infection rates increased linearly from 6.7 to 18.4 per 1000 discharges (0.83 to 1.72 episodes per 1000 patient-days) during the 12-year study period (r=87).

    Increases in the infection rates were due to gram-positive cocci (r=96) and yeasts (r=95) and essentially explained by infections caused by coagulase-negative staphylococci, Staphylococcus aureus, enterococci, and Candida species, respectively.

    Although the crude mortality in patients with nosocomial bloodstream infections decreased from 51% in 1981 to 29% in 1992, the in-hospital population-attributable mortality among infected patients increased from 3.55 deaths per 1000 discharges in 1981 to 6.22 per 1000 discharges in 1992 (r=67).

    Mots-clés Pascal : Mortalité, Incidence, Etiologie, Facteur risque, Homme, Hôpital, Infection nosocomiale

    Mots-clés Pascal anglais : Mortality, Incidence, Etiology, Risk factor, Human, Hospital

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0363546

    Code Inist : 002B30A02C. Création : 01/03/1996.