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  1. Blood-borne virus infections among Australian injecting drug users : implications for spread of HIV.

    Article - En anglais

    To describe the epidemiology of infection with hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV) among injecting drug users (IDUs) in Australia, in relation to the potential for further spread of HIV in IDUs, a cross-sectional analysis was performed on data from a sample of injecting drug users, correlating markers of exposure to blood-borne viruses with sex, age, sexual orientation, primary current drug injected and duration of injecting in rural and metropolitan Victoria, Australia.

    By multivariate analysis, HIV seropositivity was strongly associated with a history of homosexual contact in males and with exposure to HBV but not to HCV.

    Those who reported their current primary injected drug to be amphetamines were at greater and continuing risk of HIV infection than were current heroin injectors, while the reverse applied for HCV.

    The different patterns of exposure to different blood-borne viruses in this particular population of IDUs probably reflects different interactions among different social networks.

    HCV exposure provides a good surrogate marker for risk behaviour among these IDUs, but HBV exposure provides a better marker for risk of HIV infection.

    More detailed surveillance strategies for HIV infection, and more targeted HIV prevention programs are necessary to detect and to prevent further spread of HIV in these populations.

    Mots-clés Pascal : Hépatite virale B, Virose, Infection, Hépatite virale C, SIDA, Epidémiologie, Toxicomanie, Voie intraveineuse, Sérologie, Prévalence, Homme, Sexe, Age, Comportement sexuel, Australie, Océanie, Appareil digestif pathologie, Foie pathologie, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Viral hepatitis C, AIDS, Epidemiology, Drug addiction, Intravenous administration, Serology, Prevalence, Human, Sex, Age, Sexual behavior, Australia, Oceania, Digestive diseases, Hepatic disease, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0362427

    Code Inist : 002B05C02G. Création : 01/03/1996.