Radon and cancers other than lung cancer in underground miners : a collaborative analysis of 11 studies.
Exposure to the radioactive gas radon and its progeny (222Rn and its radioactive decay products) has recently been linked to a variety of cancers other than lung cancer in geographic correlation studies of domestic radon exposure and in individual cohorts of occupationally exposed miners.
This study was designed to characterize further the risks for cancers other than lung cancer from atmospheric radon.
Mortality from non-lung cancer was examined in a collaborative analysis of data from 11 cohorts of underground miners in which radon-related excesses of lung cancer had been established.
The study included 64 209 men who were employed in the mines for 6.4 years on average, received average cumulative exposures of 155 working-level months (WLM), and were followed for 16.9 years on average.
For all non-lung cancers combined, mortality was close to that expected from mortality rates in the areas surrounding the mines and mortality did not increase with increasing cumulative exposure.
Among 28 individual cancer categories, statistically significant increases in mortality for cancers of the stomach and statistically significant decreases for cancers of the tongue and mouth, pharynx, and colon were observed.
The increases in mortality from stomach and liver cancers and leukemia are unlikely to have been caused by radon, since they are unrelated to cumulative exposure.
Mots-clés Pascal : Tumeur maligne, Leucémie, Lymphome, Facteur risque, Exploitation minière, Exposition professionnelle, Radon, Radioisotope, Atmosphère, Epidémiologie, Homme, Hémopathie maligne, Lymphoprolifératif syndrome, Médecine travail
Mots-clés Pascal anglais : Malignant tumor, Leukemia, Lymphoma, Risk factor, Mining, Occupational exposure, Radon, Radioisotope, Atmosphere, Epidemiology, Human, Malignant hemopathy, Lymphoproliferative syndrome, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0352090
Code Inist : 002B04B. Création : 01/03/1996.