International and interethnic differences in prostate cancer incidence suggest an environmental, potentially modifiable etiology for the disease.
Our aim was to evaluate the roles of diet, physical activity patterns, body size, and migration characteristics on risk in these ethnic groups and to assess how much of the interethnic differences in risk might be attributed to interethnic differences in such life-style characteristics.
We used a common protocol and questionnaire to administer personal interviews to 1655 black, white, Chinese-American, and Japanese-American case patients diagnosed during 1987-1991 with histologically confirmed prostate carcinoma and to 1645 population-based control subjects matched to case patients by age, ethnicity, and region or residence.
Sera collected from 1127 control subjects were analyzed for levels or prostate-specific antigen (PSA) to permit comparison or case patients with control subjects lacking serological evidence or prostate disease.
Odds ratios were estimated using conditional logistic regression.
We estimated the proportion or prostate cancer attributable to certain risk factors and the proportion of interethnic risk differences attributable to interethnic differences in risk-factor prevalence.
A positive statistically significant association of prostate cancer risk and total fat intake was found for all ethnic groups combined.
Mots-clés Pascal : Tumeur maligne, Prostate, Facteur risque, Epidémiologie, Exercice physique, Régime alimentaire, Matière grasse, Taille corporelle, Ethnie, Caucasoïde, Négroïde, Asiatique, Immigration, Etats Unis, Amérique du Nord, Amérique, Canada, Homme, Prostate pathologie, Appareil urinaire pathologie, Appareil génital mâle pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Prostate, Risk factor, Epidemiology, Physical exercise, Diet, Fat, Body size, Ethnic group, Caucasoid, Negroid, Asiatic, Immigration, United States, North America, America, Canada, Human, Prostate disease, Urinary system disease, Male genital diseases, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0333049
Code Inist : 002B14D02. Création : 01/03/1996.