Passive smoking by self report and serum cotinine and the prevalence of respiratory and coronary heart disease in the Scottish heart health study.
Study objective-To explore the relationship between self reported environmental tobacco smoke exposure (or passive smoking), the serum cotinine concentration, and evidence of respiratory or coronary disease in men and women who have never smoked.
Participants-A total of 786 men and 1492 women who reported never having smoked tobacco, and who had serum cotinine concentrations below 17.5 ng/ml, the cut off point for smoking « deceivers », took part.
Fewer than one third of never smokers reported no recent exposure to environmental tobacco smoke and the same proportion had no detectable cotinine.
Women had lower cotinine values than men but reported more exposure to smoke.
The correlation between the measures of exposure was poor.
Self reported exposure showed strong, statistically significant, dose response relationships with respiratory symptoms and with the coronary disease markers.
Here the dose response gradient was as strong as that for selfreport, with an odds ratio of 2.7 (95% CI 1.3,5.6) for the highest upsilon the lowest exposure group, adjusted for age, housing tenure, total cholesterol, and blood pressure, and not explained by fibrinogen.
Conclusions-The validity of different measures of tobacco smoke exposure needs further investigation.
The gradient of diagnosed coronary heart disease with both self reported exposure and serum cotinine was, however, surprisingly strong, statistically significant, and unexplained by other factors.
Mots-clés Pascal : Tabagisme passif, Autoévaluation, Cotinine, Cardiopathie coronaire, Appareil respiratoire pathologie, Epidémiologie, Prévalence, Homme, Ecosse, Grande Bretagne, Royaume Uni, Europe, Etude transversale, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Passive smoking, Self evaluation, Coronary heart disease, Respiratory disease, Epidemiology, Prevalence, Human, Scotland, Great Britain, United Kingdom, Europe, Cross sectional study, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0330034
Code Inist : 002B03E. Création : 01/03/1996.