Preventing the nosocomial transmission of tuberculosis.
To study the efficacy of expanded tuberculosis infection control measures consisting primarily of administrative controls.
Descriptive case series.
University-affiliated, inner-city hospital.
Introduction of expanded tuberculosis infection control measures (including an expanded respiratory isolation policy).
The number of tuberculosis exposure episodes and skin test conversion rates of health care workers were measured before and after implementation of expanded infection control measures.
After expanded infection control measures were implemented, the number of tuberculosis exposure episodes decreased from 4.4 per month (35 episodes among 103 patient admissions for potentially infectious tuberculosis over 8 months) to 0.6 per month (18 episodes among 358 patient admissions for smear-positive pulmonary tuberculosis over 28 months) (odds ratio, 9.72 ; 95% CI, 4.99 to 19.25 [P<0.001]). The cumulative number of days per month that potentially infectious patients with tuberculosis were not in isolation decreased from 35.4 to 3.3 (P<0.001).
A concomitant decrease in tuberculin skin test conversion rates in health care workers was seen ; 6-month tuberculin skin test conversion rates decreased steadily from 3.3% (118 conversions in 3579 health care workers ; 1/92 to 6/92), 1.7%, 1.4%, 0.6%, to 0.4% (23 conversions in 5153 workers.
Infection control measures effectively prevented nosocom.
Mots-clés Pascal : Tuberculose, Poumon, Hôpital, Transmission, Prévention, Homme, Mycobactériose, Bactériose, Infection, Appareil respiratoire pathologie, Poumon pathologie
Mots-clés Pascal anglais : Tuberculosis, Lung, Hospital, Transmission, Prevention, Human, Mycobacterial infection, Bacteriosis, Infection, Respiratory disease, Lung disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0328078
Code Inist : 002B30A01C. Création : 01/03/1996.