Nutrition in early childhood and its long-term functional significance. Symposium. Anaheim CA USA, 1992/04/26.
From 1969 to 1977 a supplementation trial was conducted in Guatemala to ascertain the effects on physical and behavioral outcomes of improved nutrition in pregnant women and in presctiool children.
This paper reviews different strategies to analyze the effect of the intervention on physical growth.
One strategy compares outcomes in two villages that were randomly allocated to receive Atole, a supplement containing high amounts of protein and energy, with values in two other villages that received Fresco, a beverage containing no protein and little energy.
Both supplements contained micronutrients.
This comparison of village means gives a probability significance statement (P<0.005) that the difference in growth was because of the supplement intervention, although it does not specify the aspect of the intervention that caused the effect.
Complementary strategies increase the credibility that the effect of the supplement was nutritional.
Thus, analysis of the dose response with increasing supplement intake within the villages excludes the possibility that the above findings were the result of knowing which villages received which supplement (i.e., measuring biases).
A greater effect in those most likely to respond nutritionally also increases the credribility that the mechanism was nutritional.
In studying other behavioral and biomedical impacts of this supplementation intervention, analyses for credibility should always be included.
Mots-clés Pascal : Article synthèse, Etude longitudinale, Régime alimentaire enrichi, Protéine, Régime alimentaire hypercalorique, Développement staturopondéral, Croissance, Validation, Politique sanitaire, Pays en développement, Nutrition, Alimentation, Développement embryonnaire, Développement postnatal, Anthropométrie, Milieu rural, Guatemala, Amérique Centrale, Amérique, Mère, Age préscolaire, Enfant, Homme
Mots-clés Pascal anglais : Review, Follow up study, Supplemented diet, Proteins, High calorie diet, Somatic growth, Growth, Validation, Health policy, Developing countries, Nutrition, Feeding, Embryonic development, Postnatal development, Anthropometry, Rural environment, Guatemala, Central America, America, Mother, Preschool age, Child, Human
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0326585
Code Inist : 002B29B. Création : 01/03/1996.