To describe clinical and serologic features of Lyme borreliosis, particularly the joint abnormalities, in Russian patients.
Physicians were invited to refer patients with past or present erythema migrans to the Rheumatology Institute in Moscow ; field studies were done of residents in an area endemic for Lyme borreliosis, and a serosurvey was conducted of patients with nonspecific neurologic, cardiac, or joint symptoms.
Serologic testing was done by ELISA and Western blotting using a strain of Borrelia afzelii, a member of the B. burgdoferi sensu lato complex, recovered from ticks from study site.
Of 86 patients with erythema migrans, neurologic abnormalities developed in 26 (30%), cardiac involvement in 5 (6%), arthritis or arthralgia in 35 (41%), and acrodermatitis in 2 (2%). Joint involvement was usually characterized by one or a few brief episodes of joint swelling or pain in one large joint at a time.
In a serosurvey of 75 patients with facial palsy, atrioventricular block, or arthritis or arthralgia of uncertain cause, 6 had IgG reactivity with =5 spirochetal proteins.
Lyme borreliosis in Russia is similar to that in other parts of Europe.
Brief episodes of arthritis or arthralgia were a common feature of the illness.
Mots-clés Pascal : Lyme maladie, Borréliose, Spirochétose, Bactériose, Infection, Homme, Symptomatologie, Arthropathie, Sérologie, Epidémiologie, Russie, Eurasie, Système ostéoarticulaire pathologie
Mots-clés Pascal anglais : Lyme disease, Borrelia infection, Spirachaetosis, Bacteriosis, Infection, Human, Symptomatology, Arthropathy, Serology, Epidemiology, Russia, Eurasia, Diseases of the osteoarticular system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0326564
Code Inist : 002B05B02L6. Création : 01/03/1996.