Effects of low doses and low dose rates of external ionizing radiation : cancer mortality among nuclear industry workers in three countries.
Studies of the mortality among nuclear industry workforces have been carried out, and nationally combined analyses performed, in the U.S., the UK and Canada.
This paper presents the results of internationally combined analyses of mortality data on 95,673 workers (85.4% men) monitored for external exposure to ionizing radiation and employed for 6 months or longer in the nuclear industry of one of the three countries.
These analyses were undertaken to obtain a more precise direct assessment of the carcinogenic effects of protracted low-level exposure to external, predominantly gamma, radiation.
The combination of the data from the various studies increases the power to study associations between radiation and specific cancers.
The combined analyses covered a total of 2,124,526 person-years (PY) at risk and 15,825 deaths, 3,976 of which were due to cancer.
There was no evidence of an association between radiation dose and mortality from all causes or from all cancers.
Mortality from leukemia, excluding chronic lymphocytic leukemia (CLL) - the cause of death most strongly and consistently related to radiation dose in studies of atomic bomb survivors and other populations exposed at high dose rates-was significantly associated with cumulative external radiation dose.
(one-sided P value=0.046 ; 119 deaths).
Mots-clés Pascal : Industrie nucléaire, Maladie professionnelle, Homme, Mortalité, Irradiation ionisante, Exposition professionnelle, Monitorage, Carcinogenèse, Facteur risque, Rayonnement gamma, Dosimétrie, Grandeur excès, Médecine travail
Mots-clés Pascal anglais : Nuclear industry, Occupational disease, Human, Mortality, Ionizing irradiation, Occupational exposure, Monitoring, Carcinogenesis, Risk factor, Gamma radiation, Dosimetry, Excess parameter, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0321091
Code Inist : 002B30B01B. Création : 01/03/1996.