Differential response to early nutrition supplementation : long-term effects on height at adolescence.
The classical risk approach to predicting who benefits from an intervention is unsound because it relies on the theoretical assumption that those at risk will necessarily benefit.
A better approach to systematically test who benefits from nutrition supplementation is proposed using interactive models.
Differential effects of nutrition supplementation during early childhood on stature at adolescence were studied in 245 males and 215 females to identify determinants of long-term benefit from food supplementation.
Factors studied included family socioeconomic status (SES) and children's home diet and diarrhoea during the first 3 years of life.
Data from the INCAP supplementation trial in Guatemala and from the follow-up of the same subjects at adolescence were used.
Ordinary least squares (OLS) showed that high rates of diarrhoea in males and poor SES in females were significant determinants of benefit from supplementation at adolescence, and that the effects were mediated by length at 3 years old.
Results of two-stage least squares (2SLS) analysis showed that length at 36 months, maturation and maternal height were significant determinants of height at adolescence but SES was not.
Nutrition supplementation in early childhood has long-lasting effects on body size and the larger benefits acquired by some groups of children remain throughout early adulthood.
Mots-clés Pascal : Régime alimentaire enrichi, Enfant, Homme, Age préscolaire, Développement staturopondéral, Taille corporelle, Long terme, Biométrie corporelle, Adolescent
Mots-clés Pascal anglais : Supplemented diet, Child, Human, Preschool age, Somatic growth, Body size, Long term, Corporal biometry, Adolescent
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0319399
Code Inist : 002B29B. Création : 01/03/1996.