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  1. Changes in physical fitness and all-cause mortality : a prospective study of health and unhealthy men.

    Article - En anglais


    - To evaluate the relationship between changes in physical fitness and risk of mortality in men.


    - Prospective study, with two clinical examinations (mean interval between examinations, 4.9 years) to assess change or lack of change in physical fitness as associated with risk of mortality during follow-up after the subsequent examination (mean follow-up from subsequent examination, 5. 1 years).


    - Preventive medicine clinic.

    Study Participants

    - Participants were 9777 men given two preventive medical examinations, each of which included assessment of physical fitness by maximal exercise tests and evaluation of health status.

    Main Outcome Measures

    - All-cause (n=223) and cardiovascular disease (n=87) mortality.


    - The highest age-adjusted all-cause death rate was observed in men who were unfit at both examinations (122.0/10000 man-years) ; the lowest death rate was in men who were physically fit at both examinations (39.6/10000 man-years).

    Men who improved from unfit to fit between the first and subsequent examinations had an age-adjusted death rate of 67.7/10 000 man-years.

    This is a reduction in mortality risk of 44% (95% confidence interval, 25% to 59%) relative to men who remained unfit at both examinations.


    - Men who maintained or improved adequate physical fitness were less likely to die from all causes and from cardiovascular disease during follow-up than persistently unfit men.

    Mots-clés Pascal : Aptitude physique, Médecine préventive, Etude longitudinale, Epidémiologie, Mortalité, Homme, Mâle

    Mots-clés Pascal anglais : Physical fitness, Preventive medicine, Follow up study, Epidemiology, Mortality, Human, Male

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0281543

    Code Inist : 002B30A03A. Création : 01/03/1996.