We have examined the association between induced or spontaneous abortion and breast cancer risk in Greece.
In a hospital-based case-control study in Athens, 820 patients with confirmed breast cancer were compared with 795 orthopedic patient controls and 753 healthy visitor controls, matched to cases by age and interviewer.
Logistic regression was used to analyze the data, controlling for demographic, reproductive and nutritional variables.
Odds ratio (OR) patterns were similar for the 2 control series, which were therefore combined to increase precision of the estimates.
The risk for breast cancer was not increased for women who had a history of abortion, compared to nulliparous women with no history of abortion.
Thus ORs and 95% confidence intervals were for nulliparous women with spontaneous abortion, 1.17 (0.64-2.13) ; for nulliparous women with induced abortion, 0.98 (056-1.73) ; for parous women with noaboriton, 0.56 (0.31-1.01) ; for parous women with spontaneous abortion, 0.61 (0.33-1.14) and for parous women with induced abortion, 0.99 (0.56-1.74).
When the analysis was restricted to parous women, using parous women with no history of abortion as the baseline, ORs and 95% confidence intervals were for induced abortion before first full-term pregnancy, 2.06 (1.45-2.90) ; for induced abortion after first full-term pregnancy, 1.59 (1.24-2.04) and for spontaneous abortion, 1.10 (0.82-1.40).
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Homme, Epidémiologie, Facteur risque, Avortement, Antécédent, Grèce, Europe, Glande mammaire pathologie, Gestation pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Human, Epidemiology, Risk factor, Abortion, Antecedent, Greece, Europe, Mammary gland diseases, Pregnancy disorders, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0271010
Code Inist : 002B20E02. Création : 01/03/1996.