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  1. Congestive heart failure in dialysis patients : prevalence, incidence, prognosis and risk factors.

    Article - En anglais

    Cardiovascular disease is the most common cause of death in dialysis subjects.

    Congestive heart failure (CHF) is a common presenting symptom of cardiovascular disease in the dialysis population.

    Information regarding prevalence, incidence, risk factors and prognosis is crucial for planning rational interventional studies.

    A prospective multicenter cohort study of 432 dialysis patients followed for a mean of 41 months was carried out.

    Prospective information on a variety of risk factors was collected.

    Annual echocardiography and clinical assessment was performed.

    Major endpoints included death and the development of morbid cardiovascular events.

    One hundred and thirty-three (31%) subjects had CHF at the time of initiation of dialysis therapy.

    Multivariate analysis showed that the following risk factors were significantly and independently associated with CHF at baseline : systolic dysfunction, older age, diabetes mellitus and ischemic heart disease.

    Seventy-six of 299 subjects (25%) who did not have baseline CHF subsequently developed CHF during their course on dialysis.

    Compared to those subjects who never developed CHF (N=218) multivariate analysis identified the following risk factors for the development of CHF : older age, anemia during dialysis therapy, hypoalbuminemia, hypertension during dialysis therapy, and systolic dysfunction.

    Seventy-five of the 133 (56%) subjects with CHF at haseline had recurrent CHF during follow-up.

    Mots-clés Pascal : Insuffisance rénale, Chronique, Stade terminal, Epuration extrarénale, Homme, Complication, Insuffisance cardiaque, Prévalence, Incidence, Pronostic, Facteur risque, Epidémiologie, Appareil urinaire pathologie, Rein pathologie, Néphropathie, Appareil circulatoire pathologie, Cardiopathie

    Mots-clés Pascal anglais : Renal failure, Chronic, Terminal stade, Extrarenal dialysis, Human, Complication, Heart failure, Prevalence, Incidence, Prognosis, Risk factor, Epidemiology, Urinary system disease, Renal disease, Nephropathy, Cardiovascular disease, Heart disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0254966

    Code Inist : 002B14A05. Création : 01/03/1996.