This study identified factors predicting adherence to medical recommendations in maternal phenylketonuria, which can result in severe fetal damage.
Sixty-nine women with phenylketonuria, 68 of their acquaintances, and 69 women with diabetes mellitus were interviewed annually for 5 years.
A model in which each stage in the maternal phenylketonuria life cycle represented a treatment-related goal provided a means to assess adherence.
At the stages of prevention of unplanned pregnancy, treatment initiation, and diet continuation throughout pregnancy, attitudes and social support were associated with adherence to medical recommendations.
No specific variables were associated with outcome at reproductive decision making, but women with phenylketonuria were more likely to delay making a decision, resulting in unplanned and, hence, untreated or late-treated pregnancy.
Women with phenylketonuria differed from their acquaintances and diabetic women in many respects, suggesting that special programs are needed.
Greater emphasis on reproductive decision making is especially needed.
Interventions that focus on improving social support networks and attitudes about treatment may increase adherence to recommendations.
Mots-clés Pascal : Phénylcétonurie, Gestation, Femme, Homme, Recommandation, Observance thérapeutique, Prévention, Attitude, Support social, Connaissance, Personnalité, Etats Unis, Amérique du Nord, Amérique, Métabolisme pathologie, Aminoacidopathie, Système nerveux pathologie, Maladie héréditaire, Enzymopathie
Mots-clés Pascal anglais : Phenylketonuria, Pregnancy, Woman, Human, Recommendation, Treatment compliance, Prevention, Attitude, Social support, Knowledge, Personality, United States, North America, America, Metabolic diseases, Aminoacid disorder, Nervous system diseases, Genetic disease, Enzymopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0045164
Code Inist : 002B22D01. Création : 01/03/1996.