Vitamin B-12 status of rural Mexicans was evaluated in two studies, 6 y apart.
In the first, a single blood sample was collected from children and adults, including pregnant and lactating women.
Prevalence of deficient plasma vitamin B-12 values ranged from 19% to 41% among groups, but plasma folate status was normal in all individuals.
Breast milk vitamin B-12 concentration was low in 62% of samples.
The second study was conducted in 219 children aged 18-36 mo in five communities, whose prevalence of deficient and low plasma vitamin B-12 concentrations, respectively, was 8% and 33% on entry, 3% and 22% 6 mo later, and 7% and 29% 12 mo later.
Prevalence of low holotranscobalamin II concentrations, indicating malabsorption of the vitamin, averaged 18-40% across the three same periods.
Both vitamin B-12 status indicators differed significantly between communities.
The widespread vitamin B-12 deficiency was probably caused by malabsorption, perhaps exacerbated by low dietary intake and, for young children, maternal depletion of the vitamin.
Mots-clés Pascal : Mexique, Amérique Centrale, Amérique, Milieu rural, Nourrisson, Homme, Enfant, Adulte, Gestation, Allaitement, Prévalence, Carence vitaminique, Cyanocobalamine, Malabsorption intestinale, Carence alimentaire, Vitamine B, Malnutrition, Etat nutritionnel, Epidémiologie
Mots-clés Pascal anglais : Mexico, Central America, America, Rural environment, Infant, Human, Child, Adult, Pregnancy, Breast feeding, Prevalence, Vitamin deficiency, Cyanocobalamin, Intestinal malabsorption, Nutritional deficiency, B-Vitamins, Malnutrition, Nutritional status, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0036974
Code Inist : 002B22C. Création : 01/03/1996.