Use of an automated prescription database to identify individuals with asthma.
We used medication-dispensing information for 4 years (1/1/87 through 12/31/90) to examine the utilization of anti-asthma medications among 175,562 members of a large health maintenance organization.
A total of 297,863 anti-asthma medications was dispensed during the study period, over one-half of which (55%) were bêta-agonists, followed by aminophylline preparations (23%) and inhaled corticosteroids (13%). Next, we compared the predictive value of three algorithms for identifying individuals with asthma : (1) two or more bêta-agonist dispensings, (2) both a bêta-agonist and an inhaled corticosteroid dispensing, and (3) five or more total anti-asthma dispensings.
We performed chart reviews for 40 subjects aged 5-45 years in each of these three groups and made a clinical judgment, based on all available information in the chart, as to whether each patient had asthma.
Two levels of certainty were used : « any asthma » and « definite asthma. » All 120 charts reviewed presented a clinical picture consistent with asthma.
However, patients identified by the algorithm that included both a bêta-agonist and an inhaled corticosteroid were more likely to meet our criteria for « definite » asthma and more likely to have moderate to severe asthma.
These results demonstrate the feasibility of using an automated outpatient pharmacy database to identify patients with asthma.
Mots-clés Pascal : Antiallergique, Utilisation, Asthme, Chimiothérapie, Traitement, Base donnée, Prescription médicale, Homme, Epidémiologie, Ambulatoire, Algorithme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie, Allergie, Health maintenance organization
Mots-clés Pascal anglais : Antiallergic, Use, Asthma, Chemotherapy, Treatment, Database, Medical prescription, Human, Epidemiology, Ambulatory, Algorithm, Respiratory disease, Obstructive pulmonary disease, Immunopathology, Allergy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0024464
Code Inist : 002B02J. Création : 01/03/1996.