The relation of work-related psychologic stress to spontaneous abortion was examined in a prospective study of 3,953 pregnant, employed members of a prepaid health plan in California, recruited between 1990 and 1991.
Information on occupation, psychologic stress-related factors at work, social support at work, physical exertion at work, life events, pregnancy worries, and potential confounders was obtained by a telephone interview.
Psychologic job stress and social support at work were assessed using an abbreviated version of the instrument developed by Karasek and colleagues (Los Angeles : University of Southern California, 1986).
Results from the multivariate model indicated that, overall, stressful work was not associated with an increased risk of spontaneous abortion.
However, interactions were observed between stressful work and maternal age over 32 years (p=0.04), cigarette smoking (p=0.02), and primigravidity (p=0.06).
Relative to the odds ratio for stressful work in young, nonsmoking, multigravid women without a history of two or more spontaneous abortions, the odds ratios for spontaneous abortion given stressful work were higher by 2.45 (95% confidence interval (Cl) 1.03-5.81) for older women, 2.96 (95% Cl 1.16-7.52) for smokers, and 2.27 (95% Cl 0.97-5.27) for primigravid women.
Mots-clés Pascal : Avortement, Spontané, Femme, Homme, Epidémiologie, Exposition professionnelle, Gestation, Stress, Prospective, Californie, Etats Unis, Amérique du Nord, Amérique, Support social, Médecine travail, Gestation pathologie
Mots-clés Pascal anglais : Abortion, Spontaneous, Woman, Human, Epidemiology, Occupational exposure, Pregnancy, Stress, Prospective, California, United States, North America, America, Social support, Occupational medicine, Pregnancy disorders
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0021774
Code Inist : 002B20F02. Création : 01/03/1996.