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  1. Childhood and adolescent cancer in Spain : mortality time trends 1956-1990.

    Article - En anglais

    Using log-linear Poisson modelling, trends in childhood cancer mortality among the population under 20 years of age in Spain are described over the 35-year period from 1956 to 1990.

    Overall cancer mortality and seven specific sites were considered : all leukaemias, Hodgkin's disease, non-Hodgkin's lymphomas, malignant brain tumours, kidney cancer, malignant bone neoplasms, and a broad category of ill-defined tumours.

    An age-period-cohort model was used to analyse the influence of age, period of death and birth cohort.

    Recent trends were estimated by restricting analysis to the last three 5-year periods.

    In general, mortality began to decline at the beginning of the 1970s, with reductions of 36% in males and 45% in females being registered between 1966-1970 and 1986-1990.

    The use of age-period-cohort models revealed an initially rising period effect attributable to diagnostic advances.

    The decline in mortality in post-1965 generations and the final downturn in the period effect are both most certainly a consequence of the remarkable progress achieved in the treatment of such tumours.

    During the final 15 years, there was a relative decline in mortality of approximately 20% every 5 years.

    However, in the case of malignant renal tumours in males and malignant bone tumours and non-Hodgkin's lymphomas in both sexes the situation remained stable.

    Mots-clés Pascal : Tumeur maligne, Enfant, Homme, Adolescent, Mortalité, Espagne, Europe, Epidémiologie

    Mots-clés Pascal anglais : Malignant tumor, Child, Human, Adolescent, Mortality, Spain, Europe, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0010810

    Code Inist : 002B04B. Création : 01/03/1996.